Skin or Punch Biopsy

Skin or Punch biopsy is an investigational procedure to obtain skin specimens or to remove the lesion for laboratory analysis. This procedure is done on an outpatient basis and is usually done under local anesthesia. The skin specimen is obtained using a punch or steel blade and the wound is closed with stitches and a dressing will be applied. No stitches will be used when a shave biopsy is done.

The advantage of skin biopsy is that the dermatologist can now treat the skin problem with a definitive diagnosis after the laboratory analysis. The alternative of not doing the skin biopsy is to start treatment based on clinical diagnosis.

A lot of skin diseases are treated on the basis of clinical diagnosis e.g. eczema, psoriasis and urticaria. However, certain skin diseases mandate a skin biopsy because the treatment plan hinges on an accurate and definitive diagnosis, e.g.:

• Skin cancer concern or rapidly enlarging growth
• Blistering skin diseases
• Special situation e.g. inflammation of the fat (panniculitis), inflammation of the blood vessels (vasculitis), Kaposi sarcoma and etc

Sometimes, dermatologists can be stumped and are not sure of the clinical diagnosis. A skin biopsy will be a useful test to provide additional information.

Generally, the biopsy procedure is safe and without any side effects. However, as with any surgical procedure there are rare but possible complications as follow:

• Abnormal healing of the wound: In some people, healing of the wound may be abnormal and the wound can be thickened and become keloid. Discuss with Dr Wong if you have any concern.
• Abnormal analysis: It may turn out to be different and not the initial suspected problem. More tests with “immunostaining” may need to be done. The additional immunostaining is to help the laboratory to study the specimen/lesion better.

After a skin biopsy, most patients experience minimal discomfort or downtime and can typically return to work the same day. A wound review and dressing change are usually arranged within 1–2 days, while suture removal occurs about 7–14 days later. The biopsy report is generally ready within 5–6 days, and your good dermatologist in Singapore will review the results with you during your follow-up appointment to discuss findings and determine the next steps for treatment.

Dr Wong always tells his patients the following:

• If we are dealing with cancers, scar is our secondary concern. The primary objective is to remove all the cancerous cells and we would try to obtain as good a scar as the situation permits.
• We would avoid skin biopsy if we could proceed with treatment based on clinical diagnosis alone. Otherwise, a skin biopsy with a little scar is unavoidable.
• Dr Wong is trained in dermatology surgery and he has done biopsy on a weekly basis for 30 years. Rest assured, you are in good hands with an experienced dermatologist. He will do his best to optimise the wound healing to minimize the scar.

• A punch biopsy starts from S$1200-1800 + GST onwards
• Assurance Skin clinic follow the benchmark surgical fees set by Ministry of Health in 2024 for other types of skin biopsy / surgery