Eczema, or atopic dermatitis, is a chronic skin condition that causes inflammation, redness, and itching. Many patients experience frequent flare-ups that are difficult to control, even with the use of creams or steroids. Conventional treatments can offer short-term relief, but they may not be effective for severe cases or suitable for long-term use. Dupixent, a biologic treatment, can help manage moderate-to-severe eczema by targeting the underlying immune response.
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Dupixent (dupilumab) is a biologic medication that targets the proteins responsible for inflammation, specifically interleukin-4 (IL-4) and interleukin-13 (IL-13). By blocking these proteins, Dupixent reduces the immune response that causes eczema symptoms, leading to fewer flare-ups and improved skin conditions. Unlike topical treatments that only address skin symptoms, Dupixent works within the body to manage the root cause of eczema.
Dupixent reduces redness, itching, and the frequency of flare-ups that occur due to overactive immune responses.
Dupixent is free of steroids, avoiding side effects such as skin thinning or dependency that can occur with long-term steroid use.
Compared to oral immunosuppressants, Dupixent has zero risk with regard to internal organ side effects like kidney or liver toxicity.
Patients can administer injections at home using pre-filled syringes or pens, reducing the need for frequent clinic visits.
Below are the key characteristics of patients who may benefit from this medication:
For those whose eczema disrupts daily activities and does not respond to conventional treatments, including prescription creams and ointments.
Includes patients who have not achieved control with topical steroids or calcineurin inhibitors or cannot use them due to side effects or contraindications. This may include systemic immunosuppressive medications like azathioprine or methotrexate.
Dupixent is approved for individuals aged 12 and older with persistent eczema. Alternative treatments are needed for children under 12.
Patients with eczema and coexisting conditions such as asthma may benefit from Dupixent, as it targets shared immune pathways involved in both disorders.
If your eczema is not improving with current treatments, Dupixent may be an option. Schedule an appointment to review your symptoms and determine if this treatment is right for you.
Dupixent is generally well-tolerated, but common side effects include injection site reactions (redness, swelling), mild eye inflammation (conjunctivitis or dry eyes), and mild allergic reactions (rash, itching). Rare side effects may involve severe allergic reactions (swelling, difficulty breathing) or persistent eye inflammation that requires medical attention.
Most patients begin to see improvements in symptoms within 4 to 6 weeks of starting treatment, with continued progress over several months.
In some cases, you may be recommended to continue your existing skincare routine alongside Dupixent to manage flare-ups effectively.
If you miss a dose, administer it as soon as possible. Then, resume your regular dosing schedule without doubling the next dose.
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